A major predictor of cancer following ileorectal anastomosis

Publisher Website
Google Scholar
Abstract
Fifty patients with ulcerative colitis managed by colectomy and ileorectal anastomosis had rectal biopsies performed in the period 1967-1972. Follow-up information was available on all patients. Patients (39) were reviewed and rectal biopsies performed in the 1980-1982 period. Three patients had developed rectal cancer in the period 1975-1980, and 2 rectal cancers were detected in the 1980-1982 follow-up period. All cancers occurred in patients with a diagnosis of moderate or severe dysplasia in biopsy specimens from the 1969-1972 period. The probability of developing rectal cancer after a diagnosis of moderate or severe dysplasia in this series reached 42% at 9 yr from diagnosis.