STUDIES ON THE MALE STERILITY IN THE SILKWORM, BOMBYX MORI L., INDUCED BY APHOLATE

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Abstract
The male sterility in the silkworm Bombyx mori L. was induced with an oral administration of apholate, one of alkylating agents. Special consideration was given to cytological consequences after the treatment. When the male larvae were administered on the 1st day of the 5th instar with doses more than 300 [mu]g per insect, they were almost completely sterilized. No remarkable sterility was shown in the case of the treatment on the 5th day of the similar instar with the same doses of the chemical. The occurrence of male sterility caused by apholate was interpreted as being due mainly to the transformation of treated spermatocytes into functionless spermatozoa, on the basis of cytological observations.

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