A Comparison of Surfactant as Immediate Prophylaxis and as Rescue Therapy in Newborns of Less Than 30 Weeks' Gestation
Open Access
- 28 March 1991
- journal article
- clinical trial
- Published by Massachusetts Medical Society in New England Journal of Medicine
- Vol. 324 (13) , 865-871
- https://doi.org/10.1056/nejm199103283241301
Abstract
Exogenous pulmonary surfactants are administered into the trachea either to prevent respiratory distress syndrome in premature infants or to treat it. In a randomized, multicenter trial, we compared the results of surfactant therapy initiated as prophylaxis with the results of rescue therapy with surfactant.Keywords
This publication has 10 references indexed in Scilit:
- A Multicenter Randomized, Placebo-Controlled Trial of Surfactant Therapy for Respiratory Distress SyndromeNew England Journal of Medicine, 1989
- Surfactant Replacement Therapy for Severe Neonatal Respiratory Distress Syndrome: An International Randomized Clinical TrialPublished by American Academy of Pediatrics (AAP) ,1988
- Surfactant treatment and incidence of intraventricular haemorrhage in severe respiratory distress syndrome.Archives of Disease in Childhood, 1988
- Use of physical and neurologic observations in assessment of gestational age in low birth weight infantsThe Journal of Pediatrics, 1987
- Ten centre trial of artificial surfactant (artificial lung expanding compound) in very premature babies. Ten Centre Study Group.BMJ, 1987
- DOUBLE-BLIND CONTROLLED TRIAL OF SINGLE-DOSE TREATMENT WITH BOVINE SURFACTANT IN SEVERE HYALINE MEMBRANE DISEASEThe Lancet, 1987
- Prophylactic Treatment of Very Premature Infants with Human SurfactantNew England Journal of Medicine, 1986
- Exogenous human surfactant for treatment of severe respiratory distress syndrome: A randomized prospective clinical trialThe Journal of Pediatrics, 1985
- Surfactant substitution; experimental models and clinical applicationsLung, 1980
- Incidence and evolution of subependymal and intraventricular hemorrhage: A study of infants with birth weights less than 1,500 gmThe Journal of Pediatrics, 1978