Model Studies Indicate That Copper Phenanthroline Induces Direct Strand Breaks via β-Elimination of the 2‘-Deoxyribonolactone Intermediate Observed in Enediyne Mediated DNA Damage
- 1 April 1998
- journal article
- research article
- Published by American Chemical Society (ACS) in Journal of the American Chemical Society
- Vol. 120 (15) , 3815-3816
- https://doi.org/10.1021/ja9800075
Abstract
No abstract availableThis publication has 16 references indexed in Scilit:
- Interplay of Hydrogen Abstraction and Radical Repair in the Generation of Single- and Double-Strand DNA Damage by the EsperamicinsJournal of the American Chemical Society, 1997
- Chemical Mechanism of DNA Scission by (1,10-Phenanthroline)copper. Carbonyl Oxygen of 5-Methylenefuranone Is Derived from WaterJournal of the American Chemical Society, 1997
- Scission of DNA with Bis(1,10‐phenanthroline)copper without Intramolecular Hydrogen MigrationAngewandte Chemie International Edition in English, 1997
- Kinetics and Mechanism of the Oxidation of Sugars and Nucleotides by Oxoruthenium(IV): Model Studies for Predicting Cleavage Patterns in Polymeric DNA and RNAJournal of the American Chemical Society, 1995
- The Deoxyfucose-Anthranilate of Esperamicin A1 Confers Intercalative DNA Binding and Causes a Switch in the Chemistry of Bistranded DNA LesionsJournal of the American Chemical Society, 1994
- Selective abstraction of deuterium from C-1' of the C residue in AGC.cntdot.ICT by the radical center at C-2 of activated neocarzinostatin chromophore: structure of the drug/DNA complex responsible for bistranded lesion formationBiochemistry, 1992
- Selenoxide elimination for the synthesis of unsaturated-sugar uracil nucleosidesThe Journal of Organic Chemistry, 1991
- Isotope effects on the sequence-specific cleavage of dC in d(AGC) sequences by neocarzinostatin: elucidation of chemistry of minor lesionsJournal of the American Chemical Society, 1990
- Nuclease activity of 1,10-phenanthroline-copper ion. Chemistry of deoxyribose oxidationJournal of the American Chemical Society, 1987
- Specific Deprotonation Reactions of the Pyrimidine Radical Cation Resulting from the Menadione Mediated Photosensitization of 2′-DeoxycytidineFree Radical Research Communications, 1987