Replicative senescence of human endothelial cells in vitro involves G1 arrest, polyploidization and senescence-associated apoptosis
- 1 August 2001
- journal article
- Published by Elsevier in Experimental Gerontology
- Vol. 36 (8) , 1327-1347
- https://doi.org/10.1016/s0531-5565(01)00105-x
Abstract
No abstract availableKeywords
This publication has 47 references indexed in Scilit:
- Allosteric Activation of Acid α-Glucosidase by the Human Papillomavirus E7 ProteinJournal of Biological Chemistry, 2000
- The retinoblastoma gene family in differentiation and developmentOncogene, 1999
- Apoptosis: A Role in Skin Aging?Journal of Investigative Dermatology, 1998
- Multinucleated Variant Endothelial Cells (MVECs) in Human Aorta: Chromosomal Aneuploidy and Elevated Uptake of LDLSeminars in Thrombosis and Hemostasis, 1998
- FGF-1-dependent proliferative and migratory responses are impaired in senescent human umbilical vein endothelial cells and correlate with the inability to signal tyrosine phosphorylation of fibroblast growth factor receptor-1 substrates.The Journal of cell biology, 1996
- Increased expression of matrix metalloproteinases and matrix degrading activity in vulnerable regions of human atherosclerotic plaques.Journal of Clinical Investigation, 1994
- Evidence for a p53‐independent pathway for upregulation of SDI1/CIP1/WAF1/P21 RNA in human cellsMolecular Carcinogenesis, 1994
- Aging, longevity, and immortality in vitroExperimental Gerontology, 1992
- Extension of the Life-Span of Human Endothelial Cells by an Interleukin-1αAntisense OligomerScience, 1990
- Senescence of aortic endothelial cells in vitro: Influence of culture conditions and preliminary characterization of the senescent phenotypeMechanisms of Ageing and Development, 1982