Detection of HSV1 DNA by in situ hybridisation in human brain after immunosuppression.

Open Access

1 June 1986

journal article
research article
Published by BMJ in Journal of Neurology, Neurosurgery & Psychiatry

Vol. 49 (6) , 613-619
https://doi.org/10.1136/jnnp.49.6.613

Abstract

Human brain cells were examined for the presence of herpes simplex virus type 1 (HSV1) DNA sequences by in situ hybridisation. Viral genome was detected in immunosuppressed patients with virological evidence of past HSV infection but not in immunosuppressed patients with no such evidence. In patients who had not been immunosuppressed, no HSV DNA sequences were detectable.

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