Lack of delayed reaction in presence of cell-mediated immunity in trichophytin hypersensitivity
- 1 November 1980
- journal article
- research article
- Published by American Medical Association (AMA) in Archives of Dermatology
- Vol. 116 (11) , 1266-1268
- https://doi.org/10.1001/archderm.116.11.1266
Abstract
Five patients with atopy who had chronic dermatophytosis (due to Trichophyton) manifested an immediate and strong trichophytin skin reaction but no delayed reaction. This phenomenon may be caused by the neutralization of injected antigen by serum antibodies during the immediate reaction. When a 2nd dose of trichophytin was injected 20 min after the 1st injection into the wheal of the immediate reaction, a strong delayed reaction was elicited, demonstrating cell-mediated immune responses in these patients.This publication has 2 references indexed in Scilit:
- Immunological Capabilities of Patients with Atopic Dermatitis*Journal of Investigative Dermatology, 1966
- A propos de trichophytines sèchesInternational Archives of Allergy and Immunology, 1951