The therapeutic potential of RNA interference
Open Access
- 15 August 2005
- journal article
- review article
- Published by Wiley in FEBS Letters
- Vol. 579 (26) , 5996-6007
- https://doi.org/10.1016/j.febslet.2005.08.004
Abstract
In recent years, we have witnessed the discovery of a new mechanism of gene regulation called RNA interference (RNAi), which has revitalized interest in the development of nucleic acid‐based technolo...Keywords
This publication has 174 references indexed in Scilit:
- MicroRNA expression profiles classify human cancersNature, 2005
- c-Myc-regulated microRNAs modulate E2F1 expressionNature, 2005
- A microRNA polycistron as a potential human oncogeneNature, 2005
- The functions of animal microRNAsNature, 2004
- RNAi suppresses polyglutamine-induced neurodegeneration in a model of spinocerebellar ataxiaNature Medicine, 2004
- RETRACTED ARTICLE: EphA2: a determinant of malignant cellular behavior and a potential therapeutic target in pancreatic adenocarcinomaOncogene, 2004
- BACE1 Suppression by RNA Interference in Primary Cortical NeuronsPublished by Elsevier ,2004
- Approaches for the sequence-specific knockdown of mRNANature Biotechnology, 2003
- RNA Interference in Mammalian Cells by Chemically-Modified RNABiochemistry, 2003
- Expression profiling reveals off-target gene regulation by RNAiNature Biotechnology, 2003