ENHANCEMENT-INDUCED SPECIFIC NONREACTIVITY IN EXPERIMENTAL KIDNEY TRANSPLANTATION

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Abstract
Confirmation is presented that kidney transplantation between three weakly incompatible strains of rats leads to the formation of circulating alloantibodies. During the long survival of the kidney-grafted rats, a decline of the antibodies to background levels became evident. Kidney donor-type skin grafts were now accepted with full hair growth for several months. It is suggested that a state of autoenhancement is replaced by a specific nonreactivity.