Peptidergic (VIP) nerves in the pancreas
- 1 January 1978
- journal article
- research article
- Published by Springer Nature in Histochemistry and Cell Biology
- Vol. 55 (2) , 173-176
- https://doi.org/10.1007/bf00493519
Abstract
Vasoactive intestinal peptide (VIP) was found to occur in nerves in the pancreas of all species examined, as demonstrated by immunohistochemistry. Immunoreactive nerve terminals were seen to run in the stroma, around acini, and in the wall of blood vessels. Clusters of immunoreactive nerve cell bodies were encountered in the parenchyma; in addition other ganglia were densely innervated by VIP nerves. A particularly dense network of VIP nerves accurred in the wall of the main pancreatic duct. The present observations provide the morphological basis for accepting the action of VIP on pancreatic secretion as physiological.Keywords
This publication has 19 references indexed in Scilit:
- Vasoactive intestinal polypeptide (VIP): vesicular localization and potassium evoked release from rat hypothalamusBrain Research, 1978
- Peptidergic (vasoactive intestinal peptide) nerves in the genito-urinary tractNeuroscience, 1977
- Vasoactive Intestinal Polypeptide Occurs in Nerves of the Female Genitourinary TractScience, 1977
- Vasoactive intestinal peptide (VIP) cells in the pancreas and gastro-intestinal mucosaHistochemistry and Cell Biology, 1977
- Immunohistochemical localization of a vasodilatory polypeptide (VIP) in cerebrovascular nervesBrain Research, 1976
- Vasoactive Intestinal Polypeptide: Abundant Immunoreactivity in Neural Cell Lines and Normal Nervous TissueScience, 1976
- POSSIBLE DUAL ROLE FOR VASOACTIVE INTESTINAL PEPTIDE AS GASTROINTESTINAL HORMONE AND NEUROTRANSMITTER SUBSTANCEThe Lancet, 1976
- Diethylpyrocarbonate, a vapour-phase fixative for immunofluorescence studies on polypeptide hormonesJournal of Molecular Histology, 1974
- Isolation from Porcine‐Intestinal Wall of a Vasoactive Octacosapeptide Related to Secretin and to GlucagonEuropean Journal of Biochemistry, 1972
- Polypeptide with Broad Biological Activity: Isolation from Small IntestineScience, 1970