Intradermal Injection of Transforming Growth Factor-β1 Gene Enhances Wound Healing in Genetically Diabetic Mice
- 1 January 2003
- journal article
- Published by Springer Nature in Pharmaceutical Research
- Vol. 20 (3) , 345-350
- https://doi.org/10.1023/a:1022635600479
Abstract
Purpose. To evaluate the biologic effect of direct cutaneous TGF-β1 gene delivery on impaired wound healing models using genetically diabetic mice. Methods.Diabetic mice (C57BKS.Cg-m +/+ Leprdb...Keywords
This publication has 18 references indexed in Scilit:
- Efficient Gene Expression in Skin Wound Sites Following Local Plasmid InjectionJournal of Investigative Dermatology, 2001
- Cutaneous Wound HealingNew England Journal of Medicine, 1999
- Curcumin enhances wound healing in streptozotocin induced diabetic rats and genetically diabetic miceWound Repair and Regeneration, 1999
- Differences in Cellular Infiltrate and Extracellular Matrix of Chronic Diabetic and Venous Ulcers Versus Acute WoundsJournal of Investigative Dermatology, 1998
- Apoptosis down-regulates inflammation under the advancing epithelial wound edge: Delayed patterns in diabetes and improvement with topical growth factorsSurgery, 1997
- Apoptosis is increased in a model of diabetes-impaired wound healing in genetically diabetic miceThe International Journal of Biochemistry & Cell Biology, 1997
- Particle-mediated gene transfer with transforming growth factor-beta1 cDNAs enhances wound repair in rat skin.Journal of Clinical Investigation, 1996
- Transforming Growth Factor-β and Insulin-like Growth Factor-I in Relation to Diabetes-Induced Impairment of Wound HealingJournal of Surgical Research, 1996
- Transforming growth factor-beta stimulates wound healing and modulates extracellular matrix gene expression in pig skin: incisional wound model.1991
- PDGF AND FGF STIMULATE WOUND-HEALING IN THE GENETICALLY DIABETIC MOUSE1990