Sterilisation of Colchicine Injection
- 1 December 1963
- journal article
- Published by Oxford University Press (OUP) in Journal of Pharmacy and Pharmacology
- Vol. 15 (Supplement) , 92T-96T
- https://doi.org/10.1111/j.2042-7158.1963.tb11192.x
Abstract
Colchicine solutions for injection can be sterilised by heating at 115° for 30 min., or by heating at 98 to 100° for 30 min. in the presence of phenylmercuric nitrate 0·002 per cent, or by filtration. Solutions in multi-dose containers may be prepared using phenol 0·5 per cent, phenyhnercuric nitrate 0·001 per cent, or benzyl alcohol 1 per cent as bactericide. Sterilised solutions are stable for at least six months if protected from light.Keywords
This publication has 8 references indexed in Scilit:
- ColchicineThe American Journal of Medicine, 1961
- An X-ray diffraction determination of the chemical structure of colchicineActa Crystallographica, 1952
- Die Umwandlung des Colchicins durch SonnenlichtEuropean Journal of Inorganic Chemistry, 1951
- Structure of ColchicineNature, 1945
- NotesJournal of the Chemical Society, 1944
- The conversion of colchicine into colchiceineBiochemical Journal, 1938
- Über das ColchicinBerichte der deutschen chemischen Gesellschaft (A and B Series), 1938
- ber das ColchicinMonatshefte für Chemie / Chemical Monthly, 1886