Chronic Alveolar Hypoventilation Secondary to Macroglossia in the Beckwith-Wiedemann Syndrome

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Abstract
Chronic upper airway obstruction causes secondary reversible pulmonary hypertension. Many pathophysiologic processes can produce such obstruction. A 3-mo.-old girl with Beckwith-Wiedemann syndrome who manifested chronic upper airway obstruction secondary to macroglossia is reported. Early recognition and therapy of airway compromise may decrease morbidity and mortality in this syndrome and others in which macroglossia is present.

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