Temporoparietal Hypometabolism in Frontotemporal Lobar Degeneration and Associated Imaging Diagnostic Errors

Abstract
Frontotemporal lobar degeneration (FTLD) is the third most common degenerative dementia, behind Alzheimer disease (AD) and dementia with Lewy bodies.1 It is a heterogeneous disorder with at least 3 recognized clinical presentations,2 multiple histopathologic subtypes,3,4 and familial cases associated with mutations in 4 different genes5-9 with an additional genetic linkage on chromosome 9p.10-12