Simple methylation of amides
- 1 January 1975
- journal article
- research article
- Published by Royal Society of Chemistry (RSC) in Journal of the Chemical Society, Chemical Communications
- No. 9,p. 320-321
- https://doi.org/10.1039/c39750000320
Abstract
Reaction of amides with chloromethyl methyl sulphide in strong acid, followed by treatment with Raney nickel yields the methylamides; the preparation and activity of N2-methyl-tetracyclin are reported.Keywords
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