HLA-DR4 in ankylosing spondylitis with different patterns of joint involvement.
Open Access
- 1 January 1985
- journal article
- research article
- Published by Elsevier in Annals of the Rheumatic Diseases
- Vol. 44 (1) , 39-44
- https://doi.org/10.1136/ard.44.1.39
Abstract
Fifty patients with ankylosing spondylitis (AS) confined to the spine and sacroiliac joints were compared with 50 cases of AS complicated by various patterns of non-axial joint involvement. Radiological and clinical features were evaluated and HLA-DR4 typing was carried out. This antigen was found in 16% of 200 normal individuals in 18% of patients suffering from exclusively axial AS, and in 54% of patients with additional purely peripheral joint involvement (wrist, finger, ankle, toe). The possibility that HLA-DR4 represents a non-specific marker for peripheral arthritis in patients with ankylosing spondylitis is discussed.This publication has 14 references indexed in Scilit:
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