The etiology of severe anemia in a village and a periurban area in Mali
- 15 August 2004
- journal article
- Published by American Society of Hematology in Blood
- Vol. 104 (4) , 1198-1200
- https://doi.org/10.1182/blood-2003-11-3884
Abstract
Severe anemia is one of the major complications of malaria in Africa. We studied 2 populations, one in a village and the second in a periurban area in Mali, to understand the preventable factors in the disease. The 2 correlates of disease were parasitemia above 100 000 parasitized red blood cells per microliter (0.1 × 1012/L) and a low baseline hemoglobin level. All cases of moderate to severe anemia occurred in children under 3.2 years of age. Raising the baseline hemoglobin level and lowering peak parasitemia in infants and young children may reduce the incidence of severe anemia resulting from malarial infection. (Blood. 2004;104: 1198-1200)Keywords
This publication has 12 references indexed in Scilit:
- Effect of intermittent treatment with amodiaquine on anaemia and malarial fevers in infants in Tanzania: a randomised placebo-controlled trialThe Lancet, 2003
- Loss of Red Blood Cell–Complement Regulatory Proteins and Increased Levels of Circulating Immune Complexes Are Associated with Severe Malarial AnemiaThe Journal of Infectious Diseases, 2003
- A high malaria reinfection rate in children and young adults living under a low entomological inoculation rate in a periurban area of Bamako, Mali.The American Journal of Tropical Medicine and Hygiene, 2002
- Acute haemolysis in childhood falciparum malariaTransactions of the Royal Society of Tropical Medicine and Hygiene, 2001
- Intermittent treatment for malaria and anaemia control at time of routine vaccinations in Tanzanian infants: a randomised, placebo-controlled trialThe Lancet, 2001
- Longitudinal evaluation of severely anemic children in KenyaAIDS, 1997
- Randomised placebo-controlled trial of iron supplementation and malaria chemoprophylaxis for prevention of severe anaemia and malaria in Tanzanian infantsThe Lancet, 1997
- Indicators of Life-Threatening Malaria in African ChildrenNew England Journal of Medicine, 1995
- Malaria-a neglected disease?Parasitology, 1992
- The Anaemia of P. falciparum MalariaBritish Journal of Haematology, 1980