Reversible brain shrinkage in abstinent alcoholics, measured by MRI
- 1 November 1988
- journal article
- research article
- Published by Springer Nature in Neuroradiology
- Vol. 30 (5) , 385-389
- https://doi.org/10.1007/bf00404102
Abstract
Magnetic resonance imaging of the intracranial CSF volume was compared before and after 5 weeks of confirmed abstinence in 9 alcohol-dependent patients. All patients showed a highly significant reduction in CSF volume in accordance with reexpansion of the brain after alcohol abstinence. T2 values for white matter, estimated by linear regression from 16 echoes of a CPGM sequence, however, showed no significant increase such as occurs in rehydration. This indicates, that alcohol-induced reversible brain atrophy cannot be attributed to fluctuation of free water in the brain only.Keywords
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