THE RATE OF ESCAPE OF HEMOGLOBIN FROM THE HEMOLYZED RED CORPUSCLE
Open Access
- 20 September 1934
- journal article
- research article
- Published by Rockefeller University Press in The Journal of general physiology
- Vol. 18 (1) , 103-107
- https://doi.org/10.1085/jgp.18.1.103
Abstract
A theoretical treatment is given of the rate of escape of hemoglobin from the hemolyzed red corpuscle. For complete permeability of the surface, as may perhaps be produced by strong lysins, the time taken for the hemoglobin to decrease to 10 per cent of its original concentration is calculated to be 0.16 seconds (for the human cell). For dilute saponin, giving complete lysis of human cells in 3 minutes, Ponder found a time of escape of 4 seconds, from which the permeability of the membrane to the pigment is calculated to be µH = 5 x 10–5 cm./sec.This publication has 1 reference indexed in Scilit:
- A METHOD FOR THE DETERMINATION OF DIFFUSION CONSTANTS AND THE CALCULATION OF THE RADIUS AND WEIGHT OF THE HEMOGLOBIN MOLECULEThe Journal of general physiology, 1929