Multidisciplinary treatment of biliary tract cancers
- 1 April 1994
- journal article
- Published by Wiley in Journal of Surgical Oncology
- Vol. 55 (4) , 239-245
- https://doi.org/10.1002/jso.2930550408
Abstract
Ninety‐six patients referred for radiation therapy to Washington University affiliated institutions with tumors of the extrahepatic biliary tree form the basis of this report. Patients were examined with regard to demographic factors, tumor primary site, presenting symptoms, methods of diagnosis, and methods of management. The median survival of all 96 patients in this series was 11 months. There was no significant difference between patients with gallbladder cancer and patients with cancer of the biliary ductal system. There was a statistically significant improvement in survival in those patients undergoing resection as management or as a component of the management of their tumors (P= 0.02). Patients receiving >4,000 cGy of radiation therapy had an improved survival compared to those patients receiving ≤4,000 cGy of radiation therapy (P= 0.003). While surgical resection improved survival for those patients undergoing removal of all gross tumor, this effect was noted especially in patients with gallbladder cancer. © Wiley‐Liss, Inc.Keywords
This publication has 22 references indexed in Scilit:
- Primary carcinoma of the gallbladderJournal of Surgical Oncology, 1991
- Combined modality therapy of extrahepatic biliary system cancerInternational Journal of Radiation Oncology*Biology*Physics, 1990
- Carcinoma of the GallbladderArchives of Surgery, 1990
- Management of Proximal cholangiocarcinomas by surgical resection and radiotherapyThe American Journal of Surgery, 1990
- Primary carcinoma of the gallbladder: TNM staging and prognosisJournal of Surgical Oncology, 1988
- Carcinoma of the extrahepatic biliary system—results of primary and adjuvant radiotherapyInternational Journal of Radiation Oncology*Biology*Physics, 1987
- Prognostic Factors in Bile Duct CarcinomaAnnals of Surgery, 1981
- On distribution-free tests for equality of survival distributionsBiometrika, 1977
- Tests for trend in life table analysisBiometrika, 1975
- Maximum utilization of the life table method in analyzing survivalJournal of Chronic Diseases, 1958