RETINOIC ACID - ENHANCEMENT OF A TUMOR AND INHIBITION OF INTERFERONS ANTI-TUMOR ACTION

  • 1 January 1981
    • journal article
    • research article
    • Vol. 67  (1) , 95-97
Abstract
The effect of trans-retinoic acid on the growth of P388 lymphoid tumors in inbred female DBA/2 mice in the presence or absence of interferon (IFN) treatment was studied. This acid derivative of vitamin A enhanced local tumor growth. trans-Retinoic acid also partially reversed IFN protection against tumor growth and mortality.