Conversion of Radioactive Orotic Acid into Pyrimidine Nucleotides of Nucleic Acid by Slices of Rat Liver.

1 October 1950

journal article
research article
Published by Frontiers Media SA in Experimental Biology and Medicine

Vol. 75 (1) , 192-193
https://doi.org/10.3181/00379727-75-18141

Abstract

Slices of rat liver caused the in vitro incorporation of radioactive orotic acid into the pyrimidine nucleotides of nucleic acid, but not into purines. Separations were made with paper chromatography and ion exchange resin columns.

Keywords

LIVER, METABOLISM
NUCLEIC ACIDS
OROTIC ACID, RADIOACTIVE
PYRIMIDINES

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