OBSERVATIONS ON THE INNERVATION OF THE CORONARY VESSELS OF THE DOG

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Abstract
A method is described for determining the action of the sympathetic and parasympathetic nerves on the caliber of the coronary blood vessels in a prep. consisting of an isolated head and heart with fibrillating ventricles. In the dog it was found that the vagi carried only cholinergic coronary vasodilator fibers which were tonically active. No evidence was obtained of cholinergic coronary vasoconstrictor fibers. The stellate ganglia sent to the heart adrenergic coronary dilator and adrenergic coronary constrictor fibers, both of which were tonically active. The tonic action of the sympathetic nerves was predominantly vasoconstrictor.

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