Binaphthyl-Substituted Chiral Phosphines and Oxides from Binaphthophooles and Nucleophiles

Abstract
Binaphthophospholes 1 are the starting compounds for the synthesis of chiral phosphine oxides 3 or phosphines 4 via reaction of phospholium salts 2 with nucleophiles. The binaphthyl residue acts as a stereochemical probe for monitoring the integrity of the phosphorus stereocenter.