Ready Release of Intracellular Muramidase (Lysozyme) from Mononuclear Cells in the Skin Window Exudates

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Abstract
Muramidase, acid phosphatase and nonspecific esterase were investigated in mononuclear cells of skin window exudate in normal persons and patients with various forms of leukemia. While acid phosphatase and nonspecific esterase gradually increased, muramidase activity was reduced. Fifty hours after the onset of the experiment, most of the mononuclear cells were muramidase-negative. In monocytic leukemia, mononuclear cells appeared rapidly in the exudate. The ready liberation of muramidase may play a significant role for the increased muramidase in this type of leukemia.

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