Experimental Transfusion in Rabbits, Guinea-pigs, Rats, and Mice of Systemic Lupus Erythematosus Plasma
Open Access
- 1 March 1962
- journal article
- research article
- Published by Elsevier in Annals of the Rheumatic Diseases
- Vol. 21 (1) , 76-78
- https://doi.org/10.1136/ard.21.1.76
Abstract
Plasma transfusion experiments were carried out on 609 rabbits, guinea-pigs, rats, and mice, with plasma obtained from three patients with S. L. E. Serum from these patients had enabled the L. E.-cell phenomenon to be transferred to man and dog, but this transfer was not effected in the 609 animals, even with much greater amounts of transfused plasma, reckoned in ml./kg. body weight. In chronic experiments on 21 guinea-pigs, no L. E.-cell phenomenon was produced, even after repeated transfusions of plasma, and no change characteristic of S. L. E. was found either histologically or by laboratory investigation.Keywords
This publication has 8 references indexed in Scilit:
- Two Types of Lupus Erythematosus Cell Factor, Shown by Induced L.E. Cell Phenomenon in DogsBMJ, 1960
- Production of Lupus Erythematosus (L.E.) Cells in the Dog by the Transfusion of Systemic Lupus Erythematosus PlasmaAnnals of the Rheumatic Diseases, 1960
- Two Types of Lupus Erythematosus Cell Factor, Shown by Induced L.E. Cell Phenomenon in ManBMJ, 1959
- Production of L.E. Cells in vivo by Transfusion of Systemic Lupus Erythematosus PlasmaAnnals of the Rheumatic Diseases, 1958
- SOME FACTORS INFLUENCING THE FORMATION OF LE CELLS - A METHOD FOR ENHANCING LE CELL PRODUCTION1956
- The Mechanics of the "L.E." Cell Phenomenon, Studied with a Simplified TestBlood, 1955
- The effect of blood coagulation on L.E. cell formation.1952