Studies on Fibrinogen Turnover Before and After Whole Body X-Irradiation in the Rat.
- 1 June 1963
- journal article
- research article
- Published by Frontiers Media SA in Experimental Biology and Medicine
- Vol. 113 (2) , 346-350
- https://doi.org/10.3181/00379727-113-28363
Abstract
Summary 1. The biological half-life for in vivo screened I131 labeled rat fibrinogen injected intravenously in normal rats was found to be 1.5 days. After 6–7 days the apparent biological half-life changed to 2.7 days. 2. The apparent whole-body turnover of I131 fibrinogen after whole-body X-irradiation was the same for both irradiated and control rats. However, the data on plasma I131 fibrinogen indicate that fibrinogen leaves the vascular space at an enhanced rate after whole-body irradiation.Keywords
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