Identification and Distribution of Phenylacetic Acid in the Brain of the Rat
- 31 May 1982
- journal article
- research article
- Published by Wiley in Journal of Neurochemistry
- Vol. 38 (6) , 1532-1536
- https://doi.org/10.1111/j.1471-4159.1982.tb06629.x
Abstract
Phenylacetic acid, the major metabolite of phenylethylamine, has been identified and quantitated in rat brain regions by capillary column high-resolution gas chromatography mass spectrometry. Its distribution is heterogeneous and correlates with that of phenylethylamine. The values obtained were (ng/g ± SEM): whole brain, 31.2 ± 2.7; caudate nucleus, 64.6 ± 6.5; hypothalamus, 60.1 ± 7.4; cerebellum, 31.3 ± 2.9; brainstem, 33.1 ± 3.3, and the “rest,” 27.6 ± 3.0.Keywords
This publication has 15 references indexed in Scilit:
- Identification and Distribution of m‐ and p‐Hydroxyphenylacetic Acids in the Brain of the RatJournal of Neurochemistry, 1981
- Kinetic Measurements of the Turnover Rates of Phenylethylamine and Tryptamine In Vivo in the Rat BrainJournal of Neurochemistry, 1980
- Phenylacetic acid excretion in manAnalytical Biochemistry, 1979
- Amphetamine and 2-phenylethylamine in post-mortem Parkinsonian brain after (-)deprenyl administrationJournal Of Neural Transmission-Parkinsons Disease and Dementia Section, 1978
- Phenylacetic acid in human cerebrospinal fluid and plasma: Selected ion monitoring assayJournal of Mass Spectrometry, 1978
- Procedural difficulties in the gas-liquid chromatographic assay of the arylalkylaminesJournal of Chromatography A, 1976
- Gas chromatographic assay of phenylacetic acid in biological fluidsClinica Chimica Acta; International Journal of Clinical Chemistry, 1975
- Identification and Distribution of β-Phenylethylamine in the RatCanadian Journal of Biochemistry, 1973
- Phenethylamines in brain and liver of rats with experimentally induced phenylketonuria-like characteristicsBiochemical Journal, 1973
- REGIONAL STUDIES OF CATECHOLAMINES IN THE RAT BRAIN‐IJournal of Neurochemistry, 1966