Molecular structure in relation to oestrogenic activity: polynuclear analogues of γ : δ -di-(4-hydroxyphenyl)- n -hexane (‘hexoestrol’)

Open Access

8 May 1942

journal article
research article
Published by The Royal Society in Proceedings of the Royal Society of London. B. Biological Sciences

Vol. 130 (861) , 435-447
https://doi.org/10.1098/rspb.1942.0011

Abstract

Eight of the most interesting polynuclear groups are shown to affect profoundly the activity of "hexoestrol" on substitution for the 4-hydroxy-phenyl groups. This evidence, combined with certain previously, published results, demonstrates that "hexoestrol" is almost certainly the most active member of the most potent series of estrogens yet investigated.