OCULAR DISTURBANCES ASSOCIATED WITH EXPERIMENTAL LESIONS OF THE MESENCEPHALIC CENTRAL GRAY MATTER

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Abstract
The region around the aqueduct of Sylvius is of special interest from an ophthalmologic point of view. One has to deal here not only with the nuclei of the third and fourth cranial nerves, below the anterior and the posterior quadrigeminal body, respectively, and with their afferent fibers for the optic and the vestibular reflex, but also with descending pathways, which transmit impulses from the hypothalamic centers of the vegetative system to the cervical portion of the sympathetic system and finally the tectal region and the nuclei of the central gray matter, the function of which is still rather obscure. Clinically it is known that lesions of the region induce anomalies of the pupillary innervation, disturbances of accommodation, and convergence, conjugate deviation of the eyeballs and paralysis of associated movements, particularly in the vertical direction. The pathologic processes producing these symptoms are, unfortunately, usually not sharply limited ; they

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