INTERACTION BETWEEN PHENYLMETHANEPHOSPHONIC ACID DIETHYL ESTER AND ISOTHIOCYANATES

Abstract
Diethyl esters of 1-N-substituted thioamido-phenylmethanephosphonic acids are obtained from 0,0-diethyl phenylmethanephosphonate, sodium amide as a metallation agent and alkyl- or arylisothiocyanates. It is established that parallel reactions also occur, resulting in the formation of the respective 1,3-disubstituted thioureas and 0-ethylthiocarbamates. These represent the main reaction products in the cases when ethanephosphonic acid diethyl ester is used as a starting reagent.