L-687, 781, a new member of the papulacandin family of .BETA.-1,3-d-glucan synthesis inhibitors. I. Fermentation, isolation, and biological activity.
- 1 January 1991
- journal article
- Published by Japan Antibiotics Research Association in The Journal of Antibiotics
- Vol. 44 (1) , 45-51
- https://doi.org/10.7164/antibiotics.44.45
Abstract
A new beta-1,3-D-glucan synthesis inhibitor, L-687,781 is produced by the cultivation of Dictyochaeta simplex ATCC 20960. L-687,781 exhibits potent in vitro antifungal activity as well as anti-Pneumocystis activity in a rat model.Keywords
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