Clinical significance of isolated hippocampal volume asymmetry in childhood epilepsy
- 26 October 2004
- journal article
- Published by Wolters Kluwer Health in Neurology
- Vol. 63 (8) , 1503-1506
- https://doi.org/10.1212/01.wnl.0000142079.79612.cb
Abstract
This study defines the clinical characteristics and evolution of 16 epileptic children with hippocampal asymmetry (HA) without sclerosis on MRI. The association of a positive family history of epilepsy (11/16), low incidence of febrile seizures (2/16), and benign prognosis (seizure control in monotherapy in 11/16, mean follow-up = 4.3 years, range 1 to 10) suggest a different clinical presentation than patients with mesial temporal sclerosis. Genetic studies of these mostly French Canadian families should help confirm the existence of a distinct syndrome.Keywords
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