Hepatic Injury Possibly Induced by Verapamil

Publisher Website
Google Scholar
Abstract
VERAPAMIL hydrochloride is a calcium channel-blocking drug used to treat supraventricular tachycardia and angina pectoris. Since it produces a reduction in vascular resistance, we studied it as an antihypertensive agent. This report describes a middle-aged woman who received verapamil therapy for hypertension and who experienced hepatic dysfunction manifested by enzymatic changes and mild systemic and localized symptoms. Report of a Case The patient is a 61-year-old woman. Her history was essentially noncontributory, except for a strong family history of hyperlipidemia and hypertension. She was receiving no prescription medications. A physical examination at the time of her initial visit on March 31, 1982, confirmed the diagnosis of essential hypertension. Funduscopy showed arteriovenous nicking, and a grade 1, late systolic murmur was detected by auscultation. A chest x-ray film showed clear lung fields and a minimally widened aorta; ECG was normal. There was no peripheral edema, no hepatomegaly, no ascites, or any

This publication has 0 references indexed in Scilit: