Effect of Dietary Enrichment with Eicosapentaenoic and Docosahexaenoic Acids on in Vitro Neutrophil and Monocyte Leukotriene Generation and Neutrophil Function
- 9 May 1985
- journal article
- research article
- Published by Massachusetts Medical Society in New England Journal of Medicine
- Vol. 312 (19) , 1217-1224
- https://doi.org/10.1056/nejm198505093121903
Abstract
The effects of dietary fish-oil fatty acids on the function of the 5-lipoxygenase pathway of peripheral-blood polymorphonuclear leukocytes and monocytes were determined in seven normal subjects who supplemented their usual diet for six weeks with daily doses of triglycerides containing 3.2 g of eicosapentaenoic acid and 2.2 g of docosahexaenoic acid.This publication has 26 references indexed in Scilit:
- The biologically active leukotrienes. Biosynthesis, metabolism, receptors, functions, and pharmacology.Journal of Clinical Investigation, 1984
- Syntheses of the Leukotrienes C5, D5, and E5Archiv der Pharmazie, 1984
- Effect of docosahexaenoic acid (DHA) on arachidonic acid metabolism and platelet functionBiochemical and Biophysical Research Communications, 1983
- Leukotrienes: Mediators of Immediate Hypersensitivity Reactions and InflammationScience, 1983
- Local Effects of Synthetic Leukotrienes (LTC4, LTD4, and LTB4) in Human SkinJournal of Investigative Dermatology, 1983
- Dietary enrichment with the polyunsaturated fatty acid eicosapentaenoic acid prevents proteinuria and prolongs survival in NZB x NZW F1 mice.Journal of Clinical Investigation, 1981
- Metabolism of arachidonic acid in ionophore-stimulated neutrophils. Esterification of a hydroxylated metabolite into phospholipids.Journal of Clinical Investigation, 1979
- EICOSAPENTAENOIC ACID AND PREVENTION OF THROMBOSIS AND ATHEROSCLEROSIS?Published by Elsevier ,1978
- Difference in microviscosity induced by different cholesterol levels in the surface membrane lipid layer of normal lymphocytes and malignant lymphoma cellsJournal of Molecular Biology, 1974
- Remodeling of Granulocyte Membrane Fatty Acids During PhagocytosisJournal of Clinical Investigation, 1974