THE EFFECT OF OXYGEN PRESSURE ON THE UPTAKE OF CARBON MONOXIDE BY MAN AT SEA LEVEL AND AT ALTITUDE

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Abstract
Studies on 9 subjects at rest indicated that the rate of CO uptake was described by the following relation: [image]A per cent COHb = (pCO X duration of exposure X minute respiratory vol.) X 0.05. The rate of uptake was inversely proportional to the inspired pO2. Total barometric pressure did not affect uptake rate. The effects of minimal anoxia due to altitude sum with the slight effects of small amts. of circulating COHb to produce moderately severe symptoms.

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