Mapping in the region of Danforth's short tail and the localization of tail length modifiers.
Open Access
- 1 February 1997
- journal article
- Published by Cold Spring Harbor Laboratory in Genome Research
- Vol. 7 (2) , 108-117
- https://doi.org/10.1101/gr.7.2.108
Abstract
We have used an interspecific backcross to generate a detailed genetic map around the mouse tail and kidney developmental mutation Danforth's short tail (Sd). The map includes 14 simple sequence repeat (SSR) markers and four genes in a 5-cM region encompassing Sd. In addition we have used a DNA pooling approach to carry out a genome scan to localize quantitative trait loci (QTL) that modify the tail length of Sd progeny of the backcross. This has allowed us to identify a major QTL on chromosome 10 in the region of nodal and three other putative tail length QTL on chromosomes 1, 9, and 18.Keywords
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