ANTIBIOTIC SUSCEPTIBILITY TESTING OF NEISSERIA-GONORRHOEAE BY DISK-AGAR DIFFUSION

  • 1 January 1981
    • journal article
    • research article
    • Vol. B132  (1) , 23-39
Abstract
The minimal inhibitory concentrations (MIC) of 5 antibiotics against 80 strains of N. gonorrhoeae were determined by the agar dilution method using 2 different culture media. Results were compared with those obtained with the disc-agar diffusion technique. With 1 medium under defined conditions of inoculum, a close statistical correlation was found for MIC of penicillin G, cefotaxime, tetracycline and thiamphenicol, with linear regression coefficients (r) ranging from -0.9457 to -0.7400. The MIC for spectinomycin was not correlated (r = -0.2503) to those of the other antibiotics. The technique described allows easy detection of .beta.-lactamase-producing strains of gonococci.