Genetic Mapping of the Mouse Proto-Oncogene c- sis to Chromosome 15

26 August 1983

journal article
research article
Published by American Association for the Advancement of Science (AAAS) in Science

Vol. 221 (4613) , 867-869
https://doi.org/10.1126/science.6308764

Abstract

The mouse homolog (c- sis ) of the transforming gene of the simian sarcoma virus was mapped to chromosome 15 by the Southern blot analysis of DNA's from hamster-mouse somatic cell hybrids. Alterations in c- sis expression may thus play a role in the various murine neoplastic diseases characterized by rearrangements or duplications of chromosome 15.

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