ANOTHER LOOK AT ACUTE TOLERANCE TO THIOPENTONE
Open Access
- 1 October 1980
- journal article
- research article
- Published by Elsevier in British Journal of Anaesthesia
- Vol. 52 (10) , 1005-1009
- https://doi.org/10.1093/bja/52.10.1005
Abstract
The phenomenon of “acute tolerance” to thiopentone was re-examined in 82 subjects with induction doses of 2–15 mg kg−1. There was a strong positive correlation between the venous plasma thiopentone concentrations on recovery from anaesthesia and the induction dose, expressed as either mg kg−1 or mg kg−1. Recovery time was proportionately shorter with larger doses, being directly related to log10 of the plasma concentration at awakening.This publication has 0 references indexed in Scilit: