Overview of Immunological Studies on A-bomb Survivors
- 1 January 1991
- journal article
- review article
- Published by Oxford University Press (OUP) in Journal of Radiation Research
- Vol. 32 (SUPPLEMENT) , 301-309
- https://doi.org/10.1269/jrr.32.supplement_301
Abstract
Among the peripheral blood lymphocytes, T-cells and B-cells significantly decreased in number with age. Radiation exposure resulted in further significant decrease of T-cell count (but not B cells) in the elderly. T-cell response to PHA and allo-antigens also decreased with dose in the elderly group. In contrast, NK cell number and function increased with age while a significant dose effect was not observed.Keywords
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