Plasma levels and therapeutic response: The relevance to community pharmacy
- 1 September 1994
- journal article
- Published by Springer Nature in European Journal of Drug Metabolism and Pharmacokinetics
- Vol. 19 (3) , 279-281
- https://doi.org/10.1007/bf03188931
Abstract
An assessment of 26 patients, taking theophylline for COAD or asthma, was undertaken in a Belfast Community pharmacy. Patients had peak flow rate and serum theophylline concentration monitored. Based on these findings patients were counselled and, where appropriate, theophylline dosage was adjusted using a pharmacokinetic computer program. A statistically significant improvement was found between the number of patients who had a serum theophylline concentration in the therapeutic range at the initial assessment and at 3 months and 12 months. This was accompanied by a statistically significant improvement in peak expiratory flow rates.Keywords
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