Diversity-Oriented Synthesis of Polyketide Natural Products via Iterative Chemo- and Stereoselective Functionalization of Polyenoates: Development of a Unified Approach for the C(1−19) Segments of Lituarines A−C
- 15 December 2004
- journal article
- Published by American Chemical Society (ACS) in Organic Letters
- Vol. 7 (1) , 139-142
- https://doi.org/10.1021/ol047792c
Abstract
A unified, stereocontrolled synthesis of the C(1-19) segments of the lituarines A-C (1-3) has been achieved, highlighted by application of an iterative chemo- and stereoselective trienoate functionalization protocol, a strategy that holds considerable promise for the diversity oriented synthesis of polyketides.Keywords
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