Subtle Neurological Abnormalities as Risk Factors for Cognitive and Functional Decline, Cerebrovascular Events, and Mortality in Older Community-Dwelling Adults

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Abstract
Studies of apparently healthy, older community-dwelling persons have shown that subclinical diseases of different organs are associated with poor physical performance1,2 and frailty.3 In the Cardiovascular Health Study (CHS),4 a lower extent of subclinical cardiovascular disease predicted successful aging, defined as the years lived without physical and cognitive impairment, overt cardiovascular disease, cancer, and chronic obstructive pulmonary disease.