Depression of delayed hypersensitivity by pretreatment with Freund-type adjuvants. 3. Depressed arrival of lymphoid cells at recently immunized lymph nodes in mice pretreated with adjuvants.
- 1 August 1972
- journal article
- Vol. 11 (4) , 579-84
Abstract
Pretreatment of mice with Freund's complete adjuvant (FCA) or Corynebacterium parvum depresses the contact sensitivity which otherwise follows immunization with picryl chloride in FCA (PCL/FCA). In contrast, Bordetella pertussis is inactive. The hypothesis that this depression was partly due to the failure of lymph nodes immunized with PCL/FCA to collect lymphoid cells was tested. Mice were pretreated with FCA, C. parvum or B. pertussis, subsequently immunized with PCL/FCA, and injected with 51Cr-labelled normal lymph node cells.This publication has 7 references indexed in Scilit:
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