A Clinically Useful Capillary Blood-Sampling Technique for Rapid Determination of Therapeutic Levels of Theophylline

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Abstract
Two blood-sampling techniques, capillary and venous, were compared using the EMIT method. No difference was found in reproducibility. However, persistent positive bias of 0.628 micrograms/ml (p less than 0.01) was noted with the capillary sampling method. Any hemolysis that occurred in the capillary sampling technique did not significantly affect the assay.