Vulvar Intraepithelial Neoplasia (VIN): Principles of Surgical Therapy

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Abstract
Treatment of vulvar intraepithelial neoplasis (VIN) by surgical techniques versus laser ablation raises significant questions as to which is of most benefit to patients. Invasive carcinoma has been reported to be associated with VIN in 19% of cases. Representative multiple biopsies performed prior to laser ablation are not representative of the full extent of the disease. The possibility of missing the presence of invasive carcinoma, which could result in delay in diagnosis and institution of appropriate treatment is increased using this approach. Surgical excision gives improved healing and less morbid recovery. Total histological study of the excised sections allows identification of early invasive disease.

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