Induction of 3-hydroxy-3-methylglutaryl coenzyme A reductase activity in human fibroblasts incubated with compactin (ML-236B), a competitive inhibitor of the reductase
Open Access
- 1 February 1978
- journal article
- research article
- Published by Elsevier in Journal of Biological Chemistry
- Vol. 253 (4) , 1121-1128
- https://doi.org/10.1016/s0021-9258(17)38120-6
Abstract
No abstract availableThis publication has 22 references indexed in Scilit:
- The Low-Density Lipoprotein Pathway and its Relation to AtherosclerosisAnnual Review of Biochemistry, 1977
- Competitive inhibition of 3‐hydroxy‐3‐methylglutaryl coenzyme a reductase by ML‐236A and ML‐236B fungal metabolites, having hypocholesterolemic activityFEBS Letters, 1976
- Evidence for regulation of 3-hydroxy-3-methylglutaryl coenzyme A reductase activity and cholesterol synthesis in nonhepatic tissues of rat.Proceedings of the National Academy of Sciences, 1976
- Biochemistry of Polyisoprenoid BiosynthesisAnnual Review of Biochemistry, 1976
- Receptor-Mediated Control of Cholesterol MetabolismScience, 1976
- ML-236A, ML-236B, and ML-236C, new inhibitors of cholesterogensis produced by Penicillium citrinum.The Journal of Antibiotics, 1976
- Role of the low density lipoprotein receptor in regulating the content of free and esterified cholesterol in human fibroblasts.Journal of Clinical Investigation, 1975
- Regulation of sterol synthesis in cultured cells by oxygenated derivatives of cholesterolJournal of Cellular Physiology, 1975
- Esterification of Low Density Lipoprotein Cholesterol in Human Fibroblasts and Its Absence in Homozygous Familial HypercholesterolemiaProceedings of the National Academy of Sciences, 1974
- Familial hypercholesterolemia: Defective binding of lipoproteins to cultured fibroblasts associated with impaired regulation of 3-hydroxy-3-methylglutaryl coenzyme a reductase activityProceedings of the National Academy of Sciences, 1974