Silicone Intraocular Lens Implant Discoloration in Humans

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Abstract
To the Editor. —The implantation of silicone intraocular lenses (IOLs) began in the United States in 1984. To my knowledge, there have been no previously reported cases of silicone IOLs discoloring in the human eye. This letter documents the first 15 cases of silicone IOLs that have recently been discovered to be discolored. The exact incidence is unknown. The discoloration varies in intensity from a 4 + brunnescence (brown) (Figure) to a light tan to a brown discoloration of the IOL surface. The only method to ascertain whether the discoloration has reached its maximum intensity is to examine patients' eyes periodically. The IOLs involved are several models from two manufacturers (IOLAB Corp [Claremont, Calif] and STAAR Surgical Co [Monrovia, Calif]). Patient data are summarized in the Table. Careful scrutiny of the medical histories of these patients was unrevealing. There appeared to be no common thread linking any of the patients. All

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