Selective blockage of the Na+ transport path by Bay g 2821

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Abstract
A series of transport and electrophysiological experiments were carried out on rat salivery duct epithelium to study the mechanism of action of Bay g 2821 on electrolyte transport at the cellular level. On the basis of the reported data it is suggested that Bay g 2821 blocks Na+ entry into the cell at the luminal rather than at the intersitial membrane of the duct cell.

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